Are there any side effects of taking ashwagandha daily for a long time?

Yes, there are potential side effects of taking Ashwagandha daily for a long time. The details are as follows:

Gastrointestinal Issues: Ashwagandha may contain toxic components which in large amounts can disrupt gastrointestinal function, leading to symptoms like stomach discomfort, diarrhea, and vomiting.

Allergic Reactions: As a member of the Solanaceae family, ashwagandha can trigger allergic reactions in people allergic to Solanaceae plants. Symptoms may include rashes, itching, nausea, wheezing, or difficulty breathing. In severe cases, it can even be life-threatening.

Impact on the Nervous System: Ashwagandha contains substances like tropine and cocaine alkaloids. Abuse of ashwagandha may affect neurotransmitters in the human body, possibly resulting in drowsiness.

Thyroid Function Disorders: Some animal studies have shown that Ashwagandha can increase thyroid hormone production. It should be used with caution or avoided by people with thyroid conditions or those taking thyroid medications, as it may lead to excessive or insufficient thyroid hormone levels.

Liver and Kidney Damage: Long-term or excessive use of Ashwagandha may burden the liver and kidneys, affecting their function. Some Ashwagandha products may also contain cytotoxic substances like Withaferin A, which can cause liver damage when taken in excess.

Blood Coagulation Issues: Although not yet proven, it is speculated that Ashwagandha may affect blood coagulation. Special caution should be exercised by pregnant women, infants, the elderly, and those with liver function impairment.

Medication Interactions: Ashwagandha may interact with certain medications. For example, taking it with sedatives may increase drowsiness and the risk of breathing problems; using it with heart medications like digoxin may affect blood levels of the drug; and combining it with diabetes or hypertension medications may cause blood sugar or blood pressure to drop too low.

Excessive Iron Intake: Ashwagandha is rich in iron. Long-term use of Ashwagandha supplements may lead to excessive iron intake, which can cause serious health problems.

Worsening of Autoimmune Diseases: Ashwagandha may stimulate the immune system, potentially worsening the symptoms of autoimmune diseases such as rheumatoid arthritis or lupus.

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